The novel coronavirus SARS-CoV-2 is known to cause hypoxemia and acute respiratory distress syndrome (ARDS) in a significant portion of those with severe disease. Survivors of critical illness and ARDS often experience neurocognitive impairment but, to date, there is scant literature correlating radiographic hypoxic brain injury to hypoxemia related to ARDS. In this case series, we describe three cases of hypoxic brain injury seen on magnetic resonance imaging (MRI) in patients with hypoxemia secondary to COVID-19-related ARDS. The lack of severe observed hypoxemia in two of the cases suggests that unrecognized or asymptomatic hypoxemia may play a role in hypoxic brain injury related to COVID-19.

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COVID-19相关低氧血症的放射学和临床神经学表现

已知新型冠状病毒 SARS-CoV-2 会导致相当一部分重症患者出现低氧血症和急性呼吸窘迫综合征 (ARDS)。危重疾病和 ARDS 的幸存者经常会出现神经认知障碍，但迄今为止，很少有文献将影像学缺氧性脑损伤与 ARDS 相关的低氧血症联系起来。在本病例系列中，我们描述了 3 例通过磁共振成像 (MRI) 观察到的继发于 COVID-19 相关 ARDS 的低氧血症患者的缺氧性脑损伤病例。其中两例病例没有观察到严重的低氧血症，这表明未被识别或无症状的低氧血症可能在与 COVID-19 相关的缺氧性脑损伤中发挥作用。