Bacterial blight is caused by the pathogen Xanthomonas oryzae pv. oryzae (Xoo). Genome scale integrative analysis on the interaction of high and low temperatures on the molecular response signature in rice during the Xoo infection has not been conducted yet. We have analysed a unique RNA-Seq dataset generated on the susceptible rice variety IR24 under combined exposure of Xoo with low 29/21 °C (day/night) and high 35/31 °C (day/night) temperatures. Differentially regulated key genes and pathways in rice plants during both the stress conditions were identified. Differential dynamics of the regulatory network topology showed that WRKY and ERF families of transcription factors play a crucial role during signal crosstalk events in rice plants while responding to combined exposure of Xoo with low temperature vs. Xoo with high temperatures. Our study suggests that upon onset of high temperature, rice plants tend to switch its focus from defence response towards growth and reproduction.

细菌性枯萎病是由病原体黄单胞菌引起的。米（Xoo）。Xoo感染期间高温和低温对水稻分子反应特征的相互作用的基因组规模综合分析尚未进行。我们分析了在Xoo联合暴露下在易感水稻品种 IR24 上生成的独特 RNA-Seq 数据集低 29/21 °C（白天/黑夜）和高 35/31 °C（白天/黑夜）温度。鉴定了两种胁迫条件下水稻植物中差异调节的关键基因和途径。调控网络拓扑结构的差异动态表明，WRKY 和 ERF 转录因子家族在水稻植物信号串扰事件中起着至关重要的作用，同时响应低温Xoo与高温Xoo 的组合暴露。我们的研究表明，在高温开始时，水稻植物倾向于将其重点从防御反应转向生长和繁殖。