当前位置: X-MOL 学术Tetrahedron › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Photochemical addition of cyclic ethers/acetals to olefins using tBuOOtBu: Synthesis of masked ketones/aldehydes and diols
Tetrahedron ( IF 2.1 ) Pub Date : 2020-09-06 , DOI: 10.1016/j.tet.2020.131557
Mamiko Hayakawa , Rina Shimizu , Hajime Omori , Hisashi Shirota , Kou Uchida , Hiroshi Mashimo , Han Xu , Ryuusei Yamada , Seiya Niino , Yoshiki Wakame , Chuanxiang Liu , Tadashi Aoyama , Akihiko Ouchi

A fast photochemical C–C bond formation between cyclic ethers/acetals and olefins using di-tert-butyl peroxide (DTBP) was developed. This method provides easy access to 2-substituted cyclic ethers, and 2- or 4-substituted cyclic acetals. Acyl/formyl groups or diols can be obtained by the hydrolysis of the 2- or 4-substituted cyclic acetals, respectively. The reactions proceeded at room temperature and gave the expected products in good to excellent yields; efficient reactions were completed within 0.5 h at room temperature in >95% yield.



中文翻译:

使用t BuOO t Bu将环醚/缩醛光化学加成到烯烃中:掩蔽的酮/醛和二醇的合成

开发了使用二叔丁基过氧化物(DTBP)在环状醚/缩醛与烯烃之间快速形成光化学C-C键的方法。此方法可轻松获得2-取代的环醚和2-或4-取代的环缩醛。酰基/甲酰基或二醇可分别通过2-或4-取代的环状缩醛的水解获得。反应在室温下进行,得到预期的产物,收率良好至极好。在室温下0.5小时内完成高效反应,收率> 95%。

更新日期:2020-10-12
down
wechat
bug