Abstract Lanthanide doped upconversion (UC) nanoparticles show enormous potential in the biomedical field. However, the interference color emission and low photoluminescence quantum yield (PLQY) still limit its practical application. Here, we present a facile strategy to get α-NaErF4:40%Mn hollow cubic nanoparticles with single-band red emission. Furthermore, on the basis of this hollow cubic morphology, high efficiency red emission of Er3+ ions is obtained by heavy doping of the sensitizer (Yb3+ ions). The emission intensity of α-NaErF4:40%Mn, 40%Yb hollow cubic nanoparticles is 114,929 times higher than that of β-NaErF4 nanoparticles under 980 nm laser excitation, as well as the red emission intensity increase by 44 times under 808 nm laser excitation. High color pure and high luminous UC α-NaErF4:40%Mn, 40%Yb hollow cubic nanoparticles make them superior as biomarkers for in cell and vivo bioimaging. This will provide a good application prospect of UC nanoparticles in the biological field.

中文翻译：

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Mn/Yb重掺杂对空心立方α-NaErF4纳米粒子的高效上转换单红光发射

摘要 镧系掺杂上转换 (UC) 纳米粒子在生物医学领域显示出巨大的潜力。然而，干涉色发射和低光致发光量子产率（PLQY）仍然限制了其实际应用。在这里，我们提出了一种简单的策略来获得具有单带红色发射的 α-NaErF4:40%Mn 空心立方纳米粒子。此外，在这种空心立方形态的基础上，通过重掺杂敏化剂（Yb3+ 离子）获得 Er3+ 离子的高效红色发射。α-NaErF4:40%Mn、40%Yb空心立方纳米粒子在980 nm激光激发下的发射强度比β-NaErF4纳米粒子高114,929倍，在808 nm激光下红色发射强度提高44倍励磁。高色纯高发光UC α-NaErF4：40%Mn，40% Yb 空心立方纳米粒子使其成为细胞和体内生物成像的优良生物标志物。这将为UC纳米粒子在生物领域提供良好的应用前景。