This communication describes the development of a mild method for the cross-coupling of the C3-position of coumarin with an array of diazonium salts mediated by chlorophyll as a biocatalyst via visible light catalysis. A natural pigment such as chlorophyll is used as a green photosensitizer and environmentally benign catalyst. This general and easy procedure provides a transition-metal-free alternative for the formation of 3-aryl coumarin derivatives at room temperature with good to excellent yields.

中文翻译：

---

叶绿素催化的重氮盐对光化学区域选择性香豆素C–H芳基化

该交流描述了温和方法的发展，该方法用于香豆素的C3位与一系列由叶绿素作为生物催化剂介导的重氮盐通过可见光催化交叉偶联。天然色素（例如叶绿素）用作绿色光敏剂和对环境有益的催化剂。该通用且容易的步骤为室温下形成3-芳基香豆素衍生物提供了无过渡金属的替代方法，具有良好或优异的收率。