Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Its three core symptoms are social communication disorder, communication disorder, narrow interest and stereotyped repetitive behavior. The proportion of male and female autistic patients is 4:1. Many researchers have studied this phenomenon, but the mechanism is still unclear. This review mainly discusses the related mechanism from the perspective of gut microbiota and introduces the influence of gut microbiota on the difference of ASD between men and women, as well as how gut microbiota may affect the gender dimorphism of ASD through metabolite of microbiota, immunity, and genetics, which provide some useful information for those who are interested in this research and find more gender-specific treatment for autistic men and women.

中文翻译：

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肠道微生物群对自闭症谱系障碍性别偏见的影响。


自闭症谱系障碍（ASD）是一种复杂的神经发育障碍。其三大核心症状是社交障碍、交际障碍、兴趣狭隘和刻板重复行为。自闭症患者的男女比例为4:1。许多研究人员对这一现象进行了研究，但其机制仍不清楚。本文主要从肠道菌群的角度讨论相关机制，介绍肠道菌群对男女自闭症谱系障碍差异的影响，以及肠道菌群如何通过菌群代谢、免疫、和遗传学，这为那些对这项研究感兴趣的人提供了一些有用的信息，并为自闭症男性和女性找到了更多针对性别的治疗方法。