Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder. Its three core symptoms are social communication disorder, communication disorder, narrow interest and stereotyped repetitive behavior. The proportion of male and female autistic patients is 4:1. Many researchers have studied this phenomenon, but the mechanism is still unclear. This review mainly discusses the related mechanism from the perspective of gut microbiota and introduces the influence of gut microbiota on the difference of ASD between men and women, as well as how gut microbiota may affect the gender dimorphism of ASD through metabolite of microbiota, immunity, and genetics, which provide some useful information for those who are interested in this research and find more gender-specific treatment for autistic men and women.

中文翻译：

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肠道菌群对自闭症谱系障碍的性别偏见。

自闭症谱系障碍（ASD）是一种复杂的神经发育障碍。它的三个核心症状是社会交往障碍，交往障碍，兴趣狭窄和刻板的重复行为。男性和女性自闭症患者的比例为4：1。许多研究人员已经研究了这种现象，但是其机理仍不清楚。这篇综述主要从肠道菌群的角度探讨了相关的机制，并介绍了肠道菌群对男女ASD差异的影响，以及肠道菌群如何通过微生物菌群的代谢，免疫力，以及对ASD性别二态性的影响。和遗传学，为那些对这项研究感兴趣并为自闭症的男性和女性找到更多针对性别的治疗方法提供了有用的信息。