Abstract Selenium (Se) as a bioactive micronutrient could be augmented via transforming into nanoparticles (NPs), especially using biogenic protocols, for usage as an antimicrobial element. The reducing power of costus (Saussurea costus) root extract (SCE) was employed for phytosynthesis of Se-NPs through a simple and rapid protocol that included stirred mixing of 10 mM Na2SeO3 with 1.0% SCE solution for 4 h. The phytosynthesized SCE/Se-NP composite was obtained with a mean diameter of 6.13 nm and a zeta potential of −42.8 mV. Infrared analyses revealed the involvement of many SCE phytogroups in Se-NP synthesis, whereas transmission microscopy displayed well distribution and spherical shapes of the phytosynthesized NPs. The antibacterial assessments against foodborne pathogens (Escherichia coli, Salmonella typhimurium and Staphylococcus aureus) revealed the superior powers of SCE/Se-NPs and the elevated potentialities of SCE and Se-NPs for inhibition of bacterial pathogens. The scanning micrographs indicated that SCE/Se-NPs were attached to bacterial cells and led to their complete lysis/explosion with exposure prolongation. The SCE/Se-NP composites are recommended for the effective control of foodborne bacterial pathogens, applying a simple and eco-friendly phytosynthesis protocol.

中文翻译：

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使用木香提取物进行硒纳米颗粒的植物合成，用于针对食源性病原体的杀菌应用

摘要 硒 (Se) 作为一种生物活性微量营养素可以通过转化为纳米颗粒 (NPs) 来增强，特别是使用生物源协议，用作抗菌元素。木香 (Saussurea costus) 根提取物 (SCE) 的还原能力通过简单快速的方案用于 Se-NP 的植物合成，该方案包括将 10 mM Na2SeO3 与 1.0% SCE 溶液搅拌混合 4 小时。植物合成的 SCE/Se-NP 复合物的平均直径为 6.13 nm，zeta 电位为 -42.8 mV。红外分析显示许多 SCE 植物群参与 Se-NP 合成，而透射显微镜显示植物合成 NP 的良好分布和球形形状。对食源性病原体（大肠杆菌、鼠伤寒沙门氏菌和金黄色葡萄球菌）揭示了 SCE/Se-NPs 的优越能力以及 SCE 和 Se-NPs 抑制细菌病原体的潜力。扫描显微照片表明 SCE/Se-NPs 附着在细菌细胞上并导致它们完全溶解/爆炸并延长暴露时间。SCE/Se-NP 复合材料被推荐用于有效控制食源性细菌病原体，采用简单且环保的植物合成协议。