Tattooing of the skin involves repeated needle insertions to deposit ink into the dermal layer of the skin, potentially damaging eccrine sweat glands and the cutaneous vasculature. This study tested the hypothesis that reflex increases in sweat rate (SR) and cutaneous vasodilation are blunted in tattooed skin (TAT) compared to adjacent healthy skin (CON) during a passive whole-body heat stress (WBH). Ten individuals (5M, 5F) with a sufficient area of tattooed skin participated in the study. Intestinal temperature (T_int), skin temperature (T_skin), skin blood flow (laser-Doppler flux; LDF), and SR were continuously measured during normothermic baseline (34 °C water perfusing a tube-lined suit) and WBH (increased T_int 1.0 °C via 48 °C water perfusing suit). SR throughout WBH was lower for TAT compared to CON (p=0.033). Accumulated sweating responses during WBH (area under curve) were attenuated in TAT relative to CON (23.1±12.9, 26.9±14.5 mg×cm^-2, p=0.043). Sweating threshold, expressed as the onset of sweating in time or T_int from the initiation of WBH were not different between TAT and CON. Tattooing impeded the ability to obtain LDF measurements. These data suggest that tattooing functionally damages secretion mechanisms, affecting the reflex capacity of the gland to produce sweat, but does not appear to affect neural signaling to initiate sweating. Decreased sweating could impact heat dissipation especially when tattooing covers a higher percentage of body surface area and could be considered a potential long-term clinical side effect of tattooing.

中文翻译：

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在被动全身加热过程中，皮肤纹身会削弱出汗。

皮肤纹身涉及反复插入针头以将墨水沉积到皮肤的真皮层中，从而潜在地损害内分泌汗腺和皮肤脉管系统。这项研究检验了以下假设：与被动健康的全身热应激（WBH）相比，纹身皮肤（TAT）的汗水反射率（SR）和皮肤血管舒张反射减弱。十个人（5M，5F）有足够的纹身皮肤区域参加了研究。在正常体温基线（34°C的水浸入有衬里的衣服中）和WBH（升高）期间，连续测量肠道温度（T _int），皮肤温度（T _skin），皮肤血流量（激光多普勒通量； LDF）和SR Ť _INT通过48°C的水灌注服达到1.0°C）。与CON相比，整个WBH的SR中的TAT的SR较低（p = 0.033）。相对于CON，TAH减轻了WBH（曲线下面积）期间累积的出汗反应（23.1±12.9，26.9±14.5 mg×cm ^-2，p = 0.043）。出汗阈值，表示为及时出汗或T _int从开始WBH开始，TAT和CON之间没有差异。纹身阻碍了获得LDF测量值的能力。这些数据表明纹身在功能上损害了分泌机制，影响了腺体产生汗液的反射能力，但似乎并未影响神经信号来启动出汗。出汗减少可能会影响散热，尤其是当纹身覆盖较高的身体表面积百分比时，可以认为是纹身的潜在长期临床副作用。