The majority of existing medical diagnosis depends on the blood analysis in centralized sophisticated laboratories having bulky, complex, and time-consuming clinical instruments. Blood test involves invasive sample collection followed by plasma separation via centrifugation, and chemical analyses. This may prevent persons in need of urgent medical diagnosis and prompt medical attention. Wearable biosensor offers non-invasive monitoring of physiologically relevant biomarkers from biofluids and continuous tracking of real-time health status. Recent advances are much focused on electrochemical monitoring of various biomarkers from sweat samples. Such skin-interfaced sweat sensors require flexibility, stretchability and self-healing ability to match with the mechanical properties of the epidermis. The multiplexed sweat analysis coupled with wireless signal transduction provides vital information about health and fitness level of the wearer. This review focuses on the challenges, perspectives, recent advances and the technological aspects in the progress of wearable electrochemical sweat sensors.

现有的大多数医学诊断都依赖于具有庞大，复杂且耗时的临床仪器的集中化复杂实验室中的血液分析。血液测试涉及侵入性样本采集，然后通过离心分离血浆和化学分析。这可以防止需要紧急医疗诊断的人并立即就医。可穿戴式生物传感器可对生物流体中的生理相关生物标志物进行无创监测，并实时跟踪实时健康状况。最近的进展主要集中在对汗液样品中各种生物标志物进行电化学监测。这种与皮肤接触的汗液传感器需要柔韧性，可拉伸性和自我修复能力，以匹配表皮的机械性能。多路汗液分析与无线信号传导相结合，可提供有关穿戴者健康和健身水平的重要信息。这篇综述着重于可穿戴式电化学汗液传感器发展中的挑战，观点，最新进展和技术方面。