A theoretical model of the pyloric channel, approximated as a two-dimensional tube with sinusoidal corrugation, is developed to estimate the degree of resistance offered by the pylorus to transpyloric flow (gastric emptying and duodenogastric reflux) in the viscous regime. Study indicates that the resistance of the channel depends on pressure gradient, flow behavior index and channel diameter. Flow is majorly determined by the extent of luminal opening; since they scale to fourth power of the diameter for Newtonian flow, with the exponent being higher for pseudoplastic and lesser in case of dilatants relative to Newtonian fluid. At zero pressure difference, across the channel, the closing pylorus drives the aborad propulsion of the contents at the intestinal end, and at the gastric end the flow is driven along the orad direction. While no transfer of contents occur at the centre of pylorus due to zero pressure gradients, it is essential to have a non-zero pressure difference to drive the flow through the channel. The extent of pressure difference is found to linearly relate to the transpyloric flow rate. The resistive function of the pyloric channel is observed at a higher occlusion where there is a development of higher pressure barrier that is sensitive to the flow behavior index, frequency, occlusion, and contraction length.

建立了幽门通道的理论模型，近似为带有正弦波状波纹的二维管，以估计幽门在粘性状态下对跨幽门流动（胃排空和十二指肠胃返流）的抵抗程度。研究表明，通道的阻力取决于压力梯度，流动性能指标和通道直径。流量主要取决于管腔的开度。因为它们缩放到牛顿流直径的四次方，假塑性的指数较高，而相对于牛顿流体的膨胀率则较小。在零压差下，穿过通道的闭合幽门驱动肠内容物的异物推进，而在胃端，血流沿Orad方向驱动。由于零压力梯度，在幽门中心不会发生内含物的转移，但必须有一个非零压力差来驱动流经通道。发现压力差的程度与跨幽门流速呈线性关系。在较高的阻塞中观察到幽门通道的电阻功能，其中出现了对流动行为指数，频率，阻塞和收缩长度敏感的较高压力屏障。