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Comparative genomics reveals insights into characterization and distribution of quorum sensing-related genes in Shewanella algae from marine environment and clinical sources.
Comparative Immunology, Microbiology and Infectious Diseases ( IF 2.0 ) Pub Date : 2020-09-04 , DOI: 10.1016/j.cimid.2020.101545
Ying-Ju Chen,Guo-Cheng He,Jan-Fang Cheng,Yi-Tzu Lee,Yu-Hsuan Hung,Wen-Huei Chen,Yao-Ting Huang,Po-Yu Liu

Shewanella algae is not only the most commonly reported species in Shewanella human infections but also capable to inhabit a wide variety of habitats. Although there is evidence that quorum sensing is associated with bacterial adaptation to changing environmental conditions, little is known of the quorum sensing system in S. algae. In this study, we conducted the whole genome sequencing of S. algae strains and applied comparative genomics to reveal the core genome. Genes related to the quorum sensing system were identified by integrated bioinformatics analysis. S. algae harbor genes involved in all three main types of autoinducer systems. This study provides insights into the quorum sensing systems in S. algae, which might be valuable in the future study of cell behavior in S. algae.



中文翻译:

比较基因组学揭示了来自海洋环境和临床来源的希瓦氏菌藻中群体感应相关基因的特征和分布的见解。

希瓦氏菌藻类不仅是希瓦氏菌人类感染中最常报道的物种,而且能够栖息于多种生境中。尽管有证据表明群体感应与细菌适应不断变化的环境条件有关,但人们对S中的群体感应系统知之甚少。海藻。在这项研究中,我们进行了S的全基因组测序。菌株并应用比较基因组学揭示核心基因组。通过综合的生物信息学分析鉴定了与群体感应系统有关的基因。小号海藻包含与所有三种主要的自动诱导系统有关的基因。这项研究提供了对S中的群体感应系统的见解。藻类,这可能是在细胞行为今后的学习宝贵的小号海藻

更新日期:2020-09-11
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