An ultraviolet (UV) irradiation-based in situ silver nanoparticle (AgNP) synthesis approach has drawn significant attention for functionalizing a great variety of biomaterials. Here, we designed an AgNP-functionalized 3D-printed polylactic acid (PLA) composite scaffold with a green physical approach by employing the UV irradiation (1, 2, and 3 h) method without using any reducing agent or heat treatments. In situ AgNP synthesis was performed under different UV exposure times. The zeta sizer analysis results demonstrated that AgNPs were highly monodisperse with the particle size of 20 ± 2.2, 30 ± 3.6, and 50 ± 4.8 nm under various UV light exposure times. In situ synthesis of AgNPs on 3D-printed PLA scaffolds significantly changed the surface hydrophilicity of the 3D-printed scaffolds. These results showed that UV irradiation-based in situ AgNP synthesis on 3D-printed PLA scaffolds can be useful in various biomedical applications, such as cell culture scaffolds, biosensors, and wound healing applications.

基于紫外线（UV）辐照的原位银纳米粒子（AgNP）合成方法已引起人们对功能化多种生物材料的广泛关注。在这里，我们通过采用紫外线照射（1、2和3小时）方法而不使用任何还原剂或热处理，以绿色物理方法设计了一种AgNP功能化的3D打印的聚乳酸（PLA）复合支架，采用绿色物理方法。在不同的紫外线照射时间下进行原位AgNP合成。zeta粒度分析仪的分析结果表明，在各种紫外线照射时间下，AgNPs高度单分散，粒径分别为20±2.2、30±3.6和50±4.8 nm。原位在3D打印的PLA支架上合成AgNPs显着改变了3D打印的支架的表面亲水性。这些结果表明，在3D打印的PLA支架上基于UV辐射的原位AgNP合成可用于各种生物医学应用，例如细胞培养支架，生物传感器和伤口愈合应用。