Abstract A mild and convenient route for the synthesis of isoxazole derivatives has been developed using ZSM-5 as a heterogeneous catalyst. The reaction was carried out under a solvent-free condition to afford the desired products in good yields. A variety of functional groups was tolerated under the reaction conditions employed. Moreover, the heterogeneous catalyst (ZSM-5) was recovered and reused several times without significant loss of its catalytic activity. Graphical Abstract

中文翻译：

---

以ZSM-5为多相催化剂一锅三组分合成异恶唑

摘要 以ZSM-5为多相催化剂，开发了一种温和、方便的合成异恶唑衍生物的路线。该反应在无溶剂条件下进行，以良好的收率得到所需产物。在所采用的反应条件下可以容忍多种官能团。此外，多相催化剂（ZSM-5）被回收并重复使用多次，而其催化活性没有显着损失。图形概要