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One-pot three-component synthesis of isoxazole using ZSM-5 as a heterogeneous catalyst
Synthetic Communications ( IF 1.8 ) Pub Date : 2020-09-03 , DOI: 10.1080/00397911.2020.1815786
Navnath T. Hatvate 1 , Shrikant M. Ghodse 2
Affiliation  

Abstract A mild and convenient route for the synthesis of isoxazole derivatives has been developed using ZSM-5 as a heterogeneous catalyst. The reaction was carried out under a solvent-free condition to afford the desired products in good yields. A variety of functional groups was tolerated under the reaction conditions employed. Moreover, the heterogeneous catalyst (ZSM-5) was recovered and reused several times without significant loss of its catalytic activity. Graphical Abstract

中文翻译:

以ZSM-5为多相催化剂一锅三组分合成异恶唑

摘要 以ZSM-5为多相催化剂,开发了一种温和、方便的合成异恶唑衍生物的路线。该反应在无溶剂条件下进行,以良好的收率得到所需产物。在所采用的反应条件下可以容忍多种官能团。此外,多相催化剂(ZSM-5)被回收并重复使用多次,而其催化活性没有显着损失。图形概要
更新日期:2020-09-03
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