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Combined treatment of a medulla oblongata hemangioblastoma via permanent cysto-cisternal drainage and (postponed) gamma knife radiosurgery: a case report and review of the literature
International Journal of Neuroscience ( IF 2.2 ) Pub Date : 2020-09-03
Robert Bartoš, Jan Lodin, Tomas Marek, Martin Sameš, Veronika Němcová, Roman Liščák

Background: Hemangioblastomas are histologically benign tumors with a variable degree of morbidity and mortality based on various factors, including their anatomical location. The following paper illustrates a unique approach of combined therapy of a brainstem hemangioblastoma (HB) not associated with von Hippel-Lindau disease (vHLd) located in the medulla oblongata.

Case Description: A 21-year-old preschool teacher presented with vertigo, followed by dysphagia, trouble coughing, tongue paresis and headache and vomiting. Magnetic resonance imaging (MRI) revealed a large cystic lesion with a small intramural nodule located in the left anterolateral medulla oblongata directly behind the vertebral artery. The diagnosis of hemangioblastoma was supported by digital subtraction angiography.

Conclusion: Combined therapy consisted primarily of acute surgical fenestration and permanent drainage of the cystic portion of the tumor, due to symptomatic expansion. Follow-up stereotactic gamma knife radiosurgery (SRS) was performed after two years for minor progression of the tumor nodule. To the best of our knowledge, this is the first time such approach has been described in the literature for this pathology.



中文翻译:

永久性膀胱-脑池引流和(推迟)伽玛刀放射治疗联合治疗延髓延髓血管母细胞瘤:一例病例并文献复习

背景:血管母细胞瘤是组织学上良性肿瘤,其发病率和死亡率因各种因素而异,包括其解剖位置。以下论文说明了与长延髓上的von Hippel-Lindau病(vHLd)不相关的脑干血管母细胞瘤(HB)联合治疗的独特方法。

病例描述:一名21岁的幼儿老师出现眩晕,随后出现吞咽困难,咳嗽,咳嗽,舌头轻瘫,头痛和呕吐。磁共振成像(MRI)显示了一个大的囊性病变,一个小壁内结节位于椎动脉正下方的左前延髓长圆形。数字减影血管造影支持血管母细胞瘤的诊断。

结论:由于症状扩展,联合治疗主要包括急性手术开窗术和永久性引流肿瘤的囊性部分。两年后进行了立体定向伽马刀放射外科手术(SRS),用于肿瘤结节的轻微进展。据我们所知,这是文献首次针对这种病理学描述了这种方法。

更新日期:2020-09-03
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