Food safety and quality issues are becoming increasingly important and attract much attention, requiring the development of better analytical platforms. For example, high-resolution (especially Orbitrap) mass spectrometry simultaneously offers versatile functions such as targeted/non-targeted screening while providing qualitative and quantitative information on an almost unlimited number of analytes to facilitate routine analysis and even allows for official surveillance in the food field. This review covers the current state of Orbitrap mass spectrometry (OMS) usage in food analysis based on research reported in 2012–2019, particularly highlighting the technical aspects of OMS application and the achievement of OMS-based screening and quantitative analysis in the food field. The gained insights enhance our understanding of state-of-the-art high-resolution mass spectrometry and highlight the challenges and directions of future research.

食品安全和质量问题变得越来越重要，并引起了广泛关注，需要开发更好的分析平台。例如，高分辨率（尤其是Orbitrap）质谱仪可同时提供多种功能，例如目标/非目标筛查，同时提供几乎无限数量的分析物的定性和定量信息，以促进常规分析，甚至可以对食品进行正式监控领域。这篇综述基于2012-2019年的研究报道了食品分析中Orbitrap质谱（OMS）的使用现状，特别强调了OMS应用的技术方面以及在食品领域基于OMS的筛选和定量分析的成就。