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Thelazia rhodesi in a dairy farm in Romania and successful treatment using eprinomectin.
Parasitology International ( IF 1.5 ) Pub Date : 2020-09-03 , DOI: 10.1016/j.parint.2020.102183
Georgiana Deak 1 , Angela Monica Ionică 2 , Nicuşor-Valentin Oros 1 , Călin Mircea Gherman 1 , Andrei Daniel Mihalca 1
Affiliation  

Bovine thelaziosis can be caused by Thelazia rhodesi Desmarest 1828, Thelazia gulosa Railliet & Henry 1910 and Thelazia skrjabini Erschow 1928 which are known to be transmitted by species of Muscidae. Therapeutic measures in cattle include mechanical removal of the adult parasites, followed by irrigation of the conjunctival sac with different solutions such as levamisole (1%) or administration of ivermectin (0.2 mg/kg SC), doramectin (0.2 mg/kg SC or pour-on) both with high efficacy, however, the use of such macrocyclic lactones can be problematic in lactating cattle. Nematodes harboured in the eyes of some cattle from Romania were morphologically identified as Thelazia rhodesi and the PCR analysis confirmed the diagnosis with a 98.0% nucleotide similarity for ITS1 sequence, with other sequences available in GenBank. The present paper reports the presence of T. rhodesi in cattle from a dairy farm in Romania and the recovery after treatment with eprinomectin. To the best of our knowledge this is the first report on the efficacy of eprinomectin against Thelazia spp. and the first molecular confirmation of T. rhodesi in Romania.



中文翻译:

Thelazia rhodesi在罗马尼亚的一家奶牛场中使用埃普诺菌素成功治疗。

牛黄化病可能是由罗氏菌Thelazia rhodesi Desmarest 1828,古氏Thelazia gulosa Railliet和Henry 1910和Thelazia skrjabini Erschow 1928引起的,已知它们是由麝香科动物传播。牛的治疗措施包括机械清除成年寄生虫,然后用不同的溶液冲洗左结膜囊,如左旋咪唑(1%)或伊维菌素(0.2 mg / kg SC),多拉菌素(0.2 mg / kg SC或倒入)然而,在哺乳的牛中,使用这种大环内酯可能是有问题的。罗马尼亚一些牛眼中隐藏的线虫在形态上被鉴定为罗得西亚PCR分析证实该诊断与ITS1序列具有98.0%的核苷酸相似性,与GenBank中的其他序列相似。本文报道了罗马尼亚一家奶牛场的牛中存在罗德氏梭菌,并用依普连菌素治疗后的恢复。据我们所知,这是关于依普利菌素Thelazia spp功效的首次报道。以及罗马尼亚第一个罗氏杆菌的分子鉴定

更新日期:2020-09-03
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