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Your Base Editor Might Be Flirting with Single (Stranded) DNA: Faithful On-Target CRISPR Base Editing without Promiscuous Deamination.
Molecular Cell ( IF 14.5 ) Pub Date : 2020-09-03 , DOI: 10.1016/j.molcel.2020.07.030
Scott P Collins 1 , Chase L Beisel 2
Affiliation  

Jin et al. (2020) engineered new variants of CRISPR base editors that make precise genomic edits in rice protoplasts while minimizing untargeted mutagenesis.



中文翻译:

您的碱基编辑器可能正在使用单(链)DNA:忠实的靶向 CRISPR 碱基编辑,没有混杂的脱氨基作用。

金等人。(2020) 设计了 ​​CRISPR 碱基编辑器的新变体,可在水稻原生质体中进行精确的基因组编辑,同时最大限度地减少非靶向诱变。

更新日期:2020-09-03
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