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Application of Phage-Displayed Peptides in Tumor Imaging Diagnosis and Targeting Therapy.
International Journal of Peptide Research and Therapeutics ( IF 2.0 ) Pub Date : 2020-09-03 , DOI: 10.1007/s10989-020-10108-5
Chunyan Li 1 , Jia Li 1 , Ying Xu 1 , Ying Zhan 2 , Yu Li 1 , Tingting Song 1 , Jiao Zheng 1 , Hong Yang 1
Affiliation  

Phage display is an effective and powerful technique that provides a route to discovery unique peptides targeting to tumor cells. Specifically binding peptides are considered as the valuable target directing molecule fragments with potential efficiency to improve the current tumor clinic, and offer new approaches for tumor prevention, diagnosis and treatment. We focus on the recent advances in the isolation of tumor-targeting peptides by biopanning methods, with particular emphasis on molecular imaging, and pharmaceutical targeting therapy.



中文翻译:

噬菌体展示肽在肿瘤影像诊断和靶向治疗中的应用。

噬菌体展示是一种有效且强大的技术,它为发现靶向肿瘤细胞的独特肽提供了途径。特异性结合肽被认为是具有潜在效率的有价值的靶向分子片段,以改善当前的肿瘤临床,并为肿瘤的预防、诊断和治疗提供新的途径。我们专注于通过生物淘选方法分离肿瘤靶向肽的最新进展,特别强调分子成像和药物靶向治疗。

更新日期:2020-09-03
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