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Potential Diagnostic Systems for Coronavirus Detection: a Critical Review.
Biological Procedures Online ( IF 3.7 ) Pub Date : 2020-09-01 , DOI: 10.1186/s12575-020-00134-4
Elena Ekrami 1 , Mahdi Pouresmaieli 1 , Fatemeh Barati 1 , Sahar Asghari 1 , Farzad Ramezani Ziarani 2 , Parvin Shariati 1 , Matin Mamoudifard 1
Affiliation  

Currently there are no effective anti-viral drugs for SARS-CoV-2, so the primary line of defense is to detect infected cases as soon as possible. The high rate of contagion for this virus and the highly nonspecific symptoms of the disease (Coronovirus disease 2019, (Covid-19)) that it causes, such as respiratory symptoms, cough, dyspnea, fever, and viral pneumonia, require the urgent establishment of precise and fast diagnostic tests to verify suspected cases, screen patients, and conduct virus surveillance. Nowadays, several virus detection methods are available for viral diseases, which act on specific properties of each virus or virus family, therefore, further investigations and trials are needed to find a highly efficient and accurate detection method to detect and prevent the outcomes of the disease. Hence, there is an urgent need for more and precise studies in this field. In this review, we discussed the properties of a new generation of coronaviruses (SARS-CoV-2) following routine virus detection methods and proposed new strategies and the use of potential samples for SARS-CoV-2 detection.

中文翻译:

冠状病毒检测的潜在诊断系统:批判性审查。

目前还没有针对 SARS-CoV-2 的有效抗病毒药物,因此第一道防线是尽快发现感染病例。这种病毒的高传染率和它引起的高度非特异性的疾病症状(2019 年冠状病毒病,(Covid-19)),如呼吸道症状、咳嗽、呼吸困难、发烧和病毒性肺炎,需要紧急建立精确和快速的诊断测试,以验证疑似病例、筛查患者和进行病毒监测。目前,针对病毒性疾病的病毒检测方法有多种,它们作用于每种病毒或病毒家族的特定特性,因此,需要进一步研究和试验以找到一种高效、准确的检测方法来检测和预防疾病的后果. 因此,迫切需要在这一领域进行更多和更精确的研究。在这篇综述中,我们讨论了采用常规病毒检测方法的新一代冠状病毒 (SARS-CoV-2) 的特性,并提出了新的策略以及潜在样本用于 SARS-CoV-2 检测的用途。
更新日期:2020-09-02
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