Abstract

Living organisms have vast communication networks. When an organism is stimulated, information has to be transmitted by a signal messenger in order for the organism to respond to the stimulus in a biological community. N-(3-oxodecanoyl)-L-homoserine lactone (3-oxo-C12-HSL) is a messenger molecule; it is a quorum sensing (QS) material in bacteria colonies that induces apoptosis. In this study, a conductive polymer was successfully prepared using the crystal form of N-(3-oxodecanoyl)-L-homoserine lactone as a template by electrochemical polymerization and formation of composite. The realization of electrochemical polymerization in the crystal of a QS material to form polymer/QS material composite is significant in this research. 3-oxo-C12-HSL as a quorum sensing material behaves as crystal electrolyte in this experiment. This is the first example of electrochemical polymerization in the crystal structure of a QS material.

摘要

生物体拥有庞大的通讯网络。当生物体受到刺激时，信息必须由信号信使传递，以便生物体对生物群落中的刺激做出反应。N- (3-oxodecanoyl)-L-高丝氨酸内酯 (3-oxo-C12-HSL) 是一种信使分子；它是细菌菌落中的一种群体感应 (QS) 材料，可诱导细胞凋亡。在这项研究中，使用N的晶型成功制备了导电聚合物-(3-oxodecanoyl)-L-高丝氨酸内酯作为模板通过电化学聚合形成复合物。在QS材料晶体中实现电化学聚合形成聚合物/QS材料复合材料在本研究中具有重要意义。3-oxo-C12-HSL 作为群体感应材料在本实验中表现为晶体电解质。这是 QS 材料晶体结构中电化学聚合的第一个例子。