A novel effective chemosensor HPHN, (E)-6-hydroxy-N′-((2-hydroxynaphthalen-1-yl)methylene) picolinohydrazide, was synthesized. HPHN sensed Fe^3+/2+ with the changes of color from yellow to orange without obvious inhibition from other cations. In addition, HPHN could detect ClO⁻ by both the color change from yellow to colorless and the fluorescence quenching. The binding modes of HPHN with Fe^3+/2+ and ClO⁻ were determined to be 1:1 with Job plot and ESI-mass analysis. HPHN displayed low detection limits of 0.29 μM for Fe³⁺ and 0.77 μM for Fe²⁺. For ClO⁻, the detection limit was 6.20 μM by colorimetric method and 3.99 μM by fluorescent one, respectively. Moreover, HPHN can be employed to quantify Fe³⁺ and ClO⁻ in environmental samples and apply to cell imaging for ClO⁻.

合成了一种新型的有效化学传感器HPHN，（E）-6-羟基-N'-（（（2-羟基萘-1-基）亚甲基）甲基吡啶酰肼。HPHN感知到Fe ^{3 + / 2 +}的颜色从黄色变为橙色，而不受其他阳离子的明显抑制。此外，HPHN可以检测CLO ^-从黄色到无色两种颜色变化和荧光猝灭。的结合模式HPHN为Fe ^{3 + / 2 +}和C10 ^-被确定为1：1的工作曲线图和ESI-质谱分析。HPHN对Fe ^3+的检测限低至0.29μM，对于Fe ^2+的检测限低至0.77μM。对于ClO^-，比色法的检测限为6.20μM，荧光法为3.99μM。此外，HPHN可以采用以量化的Fe ³⁺和C10 ^-环境样品中，并适用于细胞成像CLO ^- 。