All living beings have an optimal temperature for growth and survival. With the advancement of global warming, the search for understanding adaptive processes to climate changes has gained prominence. In this context, all living beings monitor the external temperature and develop adaptive responses to thermal variations. These responses ultimately change the functioning of the cell and affect the most diverse structures and processes. One of the first structures to detect thermal variations is the plasma membrane, whose constitution allows triggering of intracellular signals that assist in the response to temperature stress. Although studies on this topic have been conducted, the underlying mechanisms of recognizing thermal changes and modifying cellular functioning to adapt to this condition are not fully understood. Recently, many reports have indicated the participation of sphingolipids (SLs), major components of the plasma membrane, in the regulation of the thermal stress response. SLs can structurally reinforce the membrane or/and send signals intracellularly to control numerous cellular processes, such as apoptosis, cytoskeleton polarization, cell cycle arresting and fungal virulence. In this review, we discuss how SLs synthesis changes during both heat and cold stresses, focusing on fungi, plants, animals and human cells. The role of lysophospholipids is also discussed.

所有生物都有生长和生存的最佳温度。随着全球变暖的推进，对了解气候变化的适应过程的探索变得越来越突出。在这种情况下，所有生物都会监测外部温度并对温度变化做出适应性反应。这些反应最终会改变细胞的功能并影响最多样化的结构和过程。检测热变化的第一个结构是质膜，其构造允许触发有助于响应温度压力的细胞内信号。尽管已经进行了关于该主题的研究，但尚未完全了解识别热变化和修改细胞功能以适应这种情况的潜在机制。最近，许多报告表明鞘脂（SLs）是质膜的主要成分，参与调节热应激反应。SL 可以在结构上增强膜或/和在细胞内发送信号以控制许多细胞过程，例如细胞凋亡、细胞骨架极化、细胞周期停滞和真菌毒力。在这篇综述中，我们讨论了热应激和冷应激下 SLs 的合成如何变化，重点是真菌、植物、动物和人体细胞。还讨论了溶血磷脂的作用。细胞骨架极化、细胞周期阻滞和真菌毒力。在这篇综述中，我们讨论了热应激和冷应激下 SLs 的合成如何变化，重点是真菌、植物、动物和人体细胞。还讨论了溶血磷脂的作用。细胞骨架极化、细胞周期阻滞和真菌毒力。在这篇综述中，我们讨论了热应激和冷应激下 SLs 的合成如何变化，重点是真菌、植物、动物和人体细胞。还讨论了溶血磷脂的作用。