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Resistance exercise attenuates postprandial metabolic responses to a high-fat meal similarly in younger and older men
Nutrition Research ( IF 3.4 ) Pub Date : 2020-11-01 , DOI: 10.1016/j.nutres.2020.08.012
Nathaniel D M Jenkins 1 , Nile F Banks 1 , Emily M Rogers 1 , Christina M Sciarrillo 2 , Nicholas A Koemel 2 , Ryan J Colquhoun 3 , Sam R Emerson 2
Affiliation  

This study examined whether an acute bout of resistance exercise (RE) attenuated postprandial responses to a high fat meal (HFM) similarly in younger versus older adult men, and probed relationships among skeletal muscle mass (SMM), age, the metabolic load index (MLI) response, and the improvement in the MLI elicited by RE versus CON. Eleven younger (24 ± 4y) and 9 older (61 ± 5y) men completed RE or control (CON) the night prior to a HFM. Before and 1, 3, and 5 hours after the HFM, blood triglycerides (TG), glucose (GLU), MLI, and cholesterol concentrations were quantified. Following a 7 ± 1-day washout period, participants returned and completed the opposite condition. Independent of age, TGs were 32.1 ± 27.1 mg/dL and 52.7 ± 26.8 mg/dL lower in RE than CON at 3 and 5 hours, respectively. MLI was also 24.3 to 56.9 mg/dL lower in RE than CON from 1 to 5 hours post-meal independent of age. The TG and MLI area under the curves (AUCs) were 15% to 31% lower in RE than CON. The GLU response was greater in the older than younger men at 1 to 5 hours post-meal. Moreover, the average GLU response was 5.6 ± 2.5 mg/dL lower in RE versus CON and was inversely related to SMM across the sample (r = -0.615). However, age, volume, or SMM were not related to the MLIAUC, nor to the improvement elicited by RE. Therefore, although the older men displayed a greater postprandial glucose response than the younger men, RE attenuated the postprandial metabolic response to a HFM similarly in younger and older men.

中文翻译:

在年轻和年长男性中,抗阻运动可减弱对高脂肪餐的餐后代谢反应

这项研究检查了急性抗阻运动 (RE) 是否会以类似方式减弱年轻男性与老年男性对高脂肪餐 (HFM) 的餐后反应,并探讨骨骼肌质量 (SMM)、年龄、代谢负荷指数之间的关系。 MLI) 响应,以及 RE 与 CON 引起的 MLI 的改进。11 名年轻 (24 ± 4 岁) 和 9 名年长 (61 ± 5 岁) 男性在 HFM 前一天晚上完成了 RE 或控制 (CON)。在 HFM 之前和之后 1、3 和 5 小时,对血液甘油三酯 (TG)、葡萄糖 (GLU)、MLI 和胆固醇浓度进行量化。经过 7 ± 1 天的冲洗期后,参与者返回并完成了相反的条件。与年龄无关,在 3 小时和 5 小时时,RE 中的 TG 分别比 CON 低 32.1 ± 27.1 mg/dL 和 52.7 ± 26.8 mg/dL。MLI 也是 24.3 比 56。与年龄无关,饭后 1 至 5 小时的 RE 比 CON 低 9 mg/dL。RE 的 TG 和 MLI 曲线下面积 (AUC) 比 CON 低 15% 至 31%。饭后 1 至 5 小时,老年男性的 GLU 反应大于年轻男性。此外,RE 的平均 GLU 响应比 CON 低 5.6 ± 2.5 mg/dL,并且与整个样本的 SMM 呈负相关(r = -0.615)。然而,年龄、体积或 SMM 与 MLIAUC 无关,也与 RE 引起的改善无关。因此,尽管老年男性比年轻男性表现出更大的餐后葡萄糖反应,但在年轻和年长男性中,RE 减弱了对 HFM 的餐后代谢反应。饭后 1 至 5 小时,老年男性的 GLU 反应大于年轻男性。此外,RE 的平均 GLU 响应比 CON 低 5.6 ± 2.5 mg/dL,并且与整个样本的 SMM 呈负相关(r = -0.615)。然而,年龄、体积或 SMM 与 MLIAUC 无关,也与 RE 引起的改善无关。因此,尽管老年男性比年轻男性表现出更大的餐后葡萄糖反应,但在年轻和年长男性中,RE 减弱了对 HFM 的餐后代谢反应。饭后 1 至 5 小时,老年男性的 GLU 反应大于年轻男性。此外,RE 的平均 GLU 响应比 CON 低 5.6 ± 2.5 mg/dL,并且与整个样本的 SMM 呈负相关(r = -0.615)。然而,年龄、体积或 SMM 与 MLIAUC 无关,也与 RE 引起的改善无关。因此,尽管老年男性比年轻男性表现出更大的餐后葡萄糖反应,但在年轻和年长男性中,RE 减弱了对 HFM 的餐后代谢反应。
更新日期:2020-11-01
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