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Chlorophyll-catalyzed tandem oxidation /[3+2] cycloaddition reactions toward the construction of pyrrolo[2,1-a]isoquinolines under visible light
Journal of Photochemistry and Photobiology A: Chemistry ( IF 4.1 ) Pub Date : 2020-09-01 , DOI: 10.1016/j.jphotochem.2020.112877
Mehdi Koohgard , Mona Hosseini-Sarvari

Chlorophyll as a green, cheap, and affordable natural pigment was used in the one-pot synthesis of pyrrolo[2,1-a]isoquinoline scaffold under visible light. This photocatalytic approach has handled oxidation/[3 + 2] cycloaddition/aromatization cascade reaction using air as the final oxidant. Under this condition, a vast variety of N-substituted tetrahydroisoquinolines were treated with dipolarophiles in good to excellent yields.



中文翻译:

叶绿素催化串联氧化/ [3 + 2]环加成反应在可见光下对吡咯并[2,1-a]异喹啉的构建

叶绿素是一种绿色,廉价且可负担的天然色素,用于在可见光下一锅合成吡咯并[2,1-a]异喹啉骨架。这种光催化方法已经使用空气作为最终氧化剂处理了氧化/ [3 + 2]环加成/芳构化的级联反应。在这种条件下,用双极性亲和剂以良好至优异的产率处理了各种N-取代的四氢异喹啉。

更新日期:2020-09-12
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