The program of potato protection recommended by the producers of agrochemicals requires application: thiamethoxam, lambda-cyhalothrin, deltamethrin, rimsulfuron and metalaxyl. Therefore, there is a risk that these pesticides are present in tubers, thus posing a toxicological risk to the consumer. In this respect, it is necessary to monitor the presence of these compounds in edible plants. Therefore, the aim of this paper was to develop a novel, simple and robust analytical procedure for simultaneous determination of above-mentioned pesticides in potato tubers. To develop an analytical procedure that fulfills SANTE demands, quick, easy, cheap, effective, rugged and safe method and matrix solid phase dispersion technique were investigated. The final determination was conducted by liquid chromatography with tandem mass spectrometry. The obtained experimental data were analyzed by analysis of variance. For the extraction of analytes, matrix solid phase dispersion with octadecyl sorbent and methanol as eluent was chosen, since it provides the validation parameters according to SANTE requirements (recovery: 77–111%, relative standard deviation: 1–10%, limit of quantification: 0.9–5.0 μg/kg). This innovative analytical procedure is a practical analytical tool, which was successfully proven by applying it for target pesticides determination in potato tuber samples of different varieties randomly chosen at local markets.

中文翻译：

---

MSPD-LC-MS / MS快速测定马铃薯块茎中农药的方法。

农用化学品生产商建议的马铃薯保护计划需要应用：噻虫嗪，λ-氯氟氰菊酯，溴氰菊酯，利福磺隆和甲霜灵。因此，存在块茎中存在这些农药的风险，从而给消费者带来毒理学风险。在这方面，有必要监测食用植物中这些化合物的存在。因此，本文的目的是开发一种同时测定马铃薯块茎中上述农药的新颖，简单，可靠的分析方法。为了开发满足SANTE要求的分析方法，研究了快速，简便，廉价，有效，坚固和安全的方法以及基质固相分散技术。通过液相色谱-串联质谱法进行最终测定。通过方差分析对获得的实验数据进行分析。对于分析物的提取，选择了十八烷基吸附剂和甲醇作为洗脱液的基质固相分散体，因为它可以根据SANTE要求提供验证参数（回收率：77–111％，相对标准偏差：1-10％，定量限：0.9–5.0μg/ kg）。这种创新的分析程序是一种实用的分析工具，已通过将其用于在当地市场上随机选择的不同品种的马铃薯块茎样品中测定目标农药而得到了成功证明。77–111％，相对标准偏差：1–10％，定量限：0.9–5.0μg/ kg）。这种创新的分析程序是一种实用的分析工具，已通过将其用于在本地市场上随机选择的不同品种的马铃薯块茎样品中测定目标农药而得到了成功证明。77–111％，相对标准偏差：1–10％，定量限：0.9–5.0μg/ kg）。这种创新的分析程序是一种实用的分析工具，已通过将其用于在当地市场上随机选择的不同品种的马铃薯块茎样品中测定目标农药而得到了成功证明。