Female germ cell development is a highly complex process that includes meiosis initiation, oocyte growth recruitment, oocyte meiosis retardation and resumption and final meiotic maturation. A series of coordinated molecular signaling factors ensure successful oogenesis. The recent rapid development of high-throughput sequencing technologies allows for the dynamic omics in female germ cells, which is essential for further understanding the regulatory mechanisms of molecular events comprehensively. In this review, we summarize the current literature of multi-omics sequenced by epigenome-, transcriptome- and proteome-associated technologies, which provide valuable information for understanding the regulation of key events during female germ cell development.

中文翻译：

---

高通量测序揭示了女性生殖细胞发育的景观。

女性生殖细胞发育是一个高度复杂的过程，包括减数分裂起始、卵母细胞生长募集、卵母细胞减数分裂延迟和恢复以及最终的减数分裂成熟。一系列协调的分子信号因子确保成功的卵子发生。最近高通量测序技术的快速发展使得女性生殖细胞的动态组学成为可能，这对于进一步全面了解分子事件的调控机制至关重要。在这篇综述中，我们总结了目前通过表观基因组、转录组和蛋白质组相关技术测序的多组学文献，这些文献为理解女性生殖细胞发育过程中关键事件的调控提供了有价值的信息。