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CSynth: An Interactive Modelling and Visualisation Tool for 3D Chromatin Structure.
Bioinformatics ( IF 4.4 ) Pub Date : 2020-08-31 , DOI: 10.1093/bioinformatics/btaa757
Stephen Todd 1, 2 , Peter Todd 2 , Simon J McGowan 3 , James R Hughes 4 , Yasutaka Kakui 5 , Frederic Fol Leymarie 1, 2 , William Latham 1, 2 , Stephen Taylor 3
Affiliation  

The 3D structure of chromatin in the nucleus is important for gene expression and regulation. Chromosome conformation capture techniques, such as Hi-C, generate large amounts of data showing interaction points on the genome but these are hard to interpret using standard tools.

中文翻译:


CSynth:3D 染色质结构的交互式建模和可视化工具。



细胞核中染色质的 3D 结构对于基因表达和调控非常重要。染色体构象捕获技术(例如 Hi-C)可生成大量数据,显示基因组上的相互作用点,但使用标准工具很难解释这些数据。
更新日期:2020-09-01
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