CXCL17, the last described chemokine, has recently been found to be abundantly and specifically expressed in mucosal sites, while its receptor is still not well determined. Accumulative studies indicate that CXCL17 could potentially exhibit chemotactic, anti‐inflammatory, antimicrobial activities under multiple biological conditions. However, the mechanism by which it contributes to the physiological and pathological processes within specific mucosal tissues is still far from being fully elucidated. In this present review, we therefore summarize the current available evidence of CXCL17 with specific emphasis on its biological role and pathophysiological significance, in order to aid in the advancement of CXCL17‐related studies.

中文翻译：

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粘膜趋化因子CXCL17：已知和未知

最近发现，CXCL17是最后描述的趋化因子，在粘膜部位大量表达并特异性表达，而其受体仍未确定。累积研究表明，CXCL17在多种生物学条件下可能具有趋化，抗炎，抗菌活性。但是，它对特定粘膜组织内的生理和病理过程所起的作用机制仍远未得到充分阐明。因此，在本综述中，我们总结了CXCL17的现有证据，特别强调了其生物学作用和病理生理学意义，以协助CXCL17相关研究的发展。