Herein, a novel phenolphthalein-derived Schiff base fluorescence probe FF2H has readily been synthesized and applied to be fluorescence ″turn-on‶ probe for Al³⁺ sensing in aceto-nitrile (ACN) : HEPES (5.0 μM, 50/50, v/v, pH = 7). The emission response of the chemo-sensor FF2H toward Al³⁺ depends on the metal chelation-enhanced fluorescence (CHEF) effect and CHEF prevents C = N isomerisation, the excited state intra-molecular (ESIPT), and PET process of the chemosensor FF2H. FF2H–Al³⁺ complexation (1:2 stoichiometry) was revealed by Job's method and ¹H–NMR titration. The detection limit (LOD) (3σ/K) value of FF2H for Al³⁺ was estimated to be 7.0 nM, demonstrating that the chemosensor FF2H could be employed as a fluorogenic ″turn-on‶ chemosensor to effectively and selectively to recognize Al³⁺.

本文中，一种新型酚酞衍生的席夫碱荧光探针FF2H已被轻松合成，并被用作在乙腈（ACN）中检测Al ^3+的荧光“开启探针” ：HEPES（5.0μM，50/50，v / v，pH = 7）。该化学传感器的发射响应FF2H朝向的Al ³⁺取决于金属螯合增强荧光（CHEF）效果和防止CHEF C = N异构化，该化学传感器的激发态的分子内（ESIPT），和PET工艺FF2H。FF2H –Al ³⁺络合（化学计量比为1：2）通过Job方法和¹ H–NMR滴定法揭示。FF2H的检测极限（LOD）（3σ/ K）值Al ³⁺的Al 2+估计为7.0 nM，表明该化学传感器FF2H可以用作荧光“开启”化学传感器，以有效和选择性地识别Al ³⁺。