Abstract Protein fouling within a polymeric microfiltration membrane was characterized in situ and in real time with non-Faradaic electrochemical impedance spectroscopy (EIS). The polymeric membrane was prepared with a conductive gold coating, allowing the membrane surface to serve as a working electrode in a three-electrode EIS system. Utilizing the membrane surface as the working electrode allowed for differentiation between internal and external contributions to fouling. Protein fouling was able to be monitored qualitatively by observing changes in the resulting Bode and Nyquist plots and quantitatively by modeling the electrochemical system with equivalent circuit components comprised of resistive and capacitive elements. To our knowledge, this work represents the first attempt to deploy a conductive polymeric membrane as an active electrode in an EIS setup.

中文翻译：

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将电化学阻抗谱与导电膜配对用于膜污染的原位表征

摘要 使用非法拉第电化学阻抗谱 (EIS) 原位实时表征聚合物微滤膜内的蛋白质污染。聚合物膜制备有导电金涂层，允许膜表面作为三电极 EIS 系统中的工作电极。利用膜表面作为工作电极可以区分内部和外部对污垢的贡献。通过观察所得到的 Bode 和 Nyquist 图的变化，可以定性地监测蛋白质污染，并通过使用由电阻和电容元件组成的等效电路组件对电化学系统进行建模来定量监测。据我们所知，