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The Effect of a Weak Static Magnetic Field in the Range of Magnitudes from a “Zero” Field (0.01 μT) to 100 μT on the Production of Reactive Oxygen Species in Nonactivated Neutrophils
Biophysics Pub Date : 2020-05-01 , DOI: 10.1134/s0006350920030161
V. V. Novikov , E. V. Yablokova , I. A. Shaev , E. E. Fesenko

It was shown that 40-min exposure of peritoneal neutrophils to hypomagnetic conditions (with a residual field of 0.01 μT) caused a significant (25%) decrease in the intensity of intracellular dichlorofluorescein fluorescence. This effect of the weak magnetic field persisted if the constant magnetic field was increased to 1 μT. Upon further increase of the field to 2.5 μT, the effect of the field disappeared and reappeared at 5 μT in a reduced form, reaching a maximum at 7 μT. There was an equally pronounced and stable inhibitory effect under a sequential increase in the induction of a constant magnetic field (9, 15, and 19.5 μT), the degree of manifestation of which was significantly reduced only at 30 μT. Fluorescence intensity of the 2,7-dichlorodydrofluorescein oxidation products did not differ from the control values at a constant magnetic field of 45 μT. There was no observed effect on these processes under further increase of the field to 74 and 100 μT.

中文翻译:

在“零”场 (0.01 μT) 到 100 μT 范围内的弱静态磁场对未活化中性粒细胞中活性氧种类产生的影响

结果表明,将腹膜中性粒细胞暴露于低磁条件(剩余磁场为 0.01 μT)40 分钟会导致细胞内二氯荧光素荧光强度显着降低(25%)。如果恒定磁场增加到 1 μT,弱磁场的这种影响就会持续存在。当磁场进一步增加到 2.5 μT 时,场效应消失并在 5 μT 处以减少的形式重新出现,在 7 μT 处达到最大值。在恒定磁场(9、15和19.5 μT)的感应连续增加下有同样显着和稳定的抑制作用,其表现程度仅在30 μT时显着降低。2、荧光强度 在 45 μT 的恒定磁场下,7-二氯三氢荧光素氧化产物与对照值没有区别。在电场进一步增加到 74 和 100 μT 的情况下,没有观察到对这些过程的影响。
更新日期:2020-05-01
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