For cementless implants, stability is initially attained by an interference fit into the bone and osteo-integration may be encouraged by coating the implant with bioactive substances. Blood based autologous glue provides an easy, cost-effective way of obtaining high concentrations of growth factors for tissue healing and regeneration with the intention of spraying it onto the implant surface during surgery. The aim of this study was to incorporate nucleated cells from autologous bone marrow (BM) aspirate into gels made from the patient's own blood, and to investigate the effects of incorporating three different concentrations of platelet rich plasma (PRP) on the proliferation and viability of the cells in the gel.

中文翻译：

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开发一种新型自体血胶，旨在改善骨-植入物界面的骨整合。

对于非骨水泥植入物，稳定性最初是通过与骨骼的过盈配合来实现的，并且可以通过在植入物上涂上生物活性物质来促进骨整合。基于血液的自体胶提供了一种简单、经济有效的方法来获得用于组织愈合和再生的高浓度生长因子，目的是在手术期间将其喷洒到植入物表面。本研究的目的是将来自自体骨髓 (BM) 抽吸物的有核细胞掺入由患者自身血液制成的凝胶中，并研究掺入三种不同浓度的富血小板血浆 (PRP) 对骨髓增殖和生存能力的影响。凝胶中的细胞。