The aim of this systematic review was to identify, evaluate, and provide a current literature about the influence of heritability on the determination of occlusal traits. MEDLINE, SCOPUS, Web of Science, LILACS, and Google Scholar were searched without restrictions up to March 2020. Studies with twin method were considered and the risk of bias assessment was performed using quality of genetic association studies checklist (Q-Genie). The coefficient of heritability (h2), model-fitting approaches, and coefficient correlation were used to estimate the genetic/environmental influence on occlusal traits. The GRADE tool was used to assess the quality of the evidence. Ten studies met the eligibility criteria. Three studies presented good quality, five moderate quality, and two poor quality. Most studies have found that the intra-arch traits, mainly the maxillary arch morphology, such as width (h2 16–100%), length (h2 42–100%), and shape (h2 42–90%), and the crowding, mainly for mandibular arch (h2 35–81%), are under potential heritability influence. The traits concerning the inter-arch relationship, as overjet, overbite, posterior crossbite, and sagittal molar relation, seem not to be genetically determined. The certainty of the evidence was graded as low for all outcomes. Although weak, the available evidence show that the heritability factors are determinant for the intra-arch traits, namely, arch morphology and crowding. Possibly due they are functionally related, the occlusal traits concerning the maxillary and mandibular relationship seem to have environmental factors as determinants. In this scenario, early preventive approaches can offer a more effective and efficient orthodontic treatment.

中文翻译：

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遗传力对咬合特性的影响：双胞胎研究的系统综述。

该系统评价的目的是鉴定，评估遗传学对确定咬合性状的影响并提供最新文献。直到2020年3月，才无限制地搜索MEDLINE，SCOPUS，Web of Science，LILACS和Google Scholar。使用双生方法进行研究，并使用基因关联研究清单（Q-Genie）的质量进行偏倚评估的风险。遗传系数（h2），模型拟合方法和系数相关性用于估计遗传/环境对咬合特性的影响。GRADE工具用于评估证据的质量。十项研究符合资格标准。三项研究的质量良好，五项质量中等，两项质量较差。大多数研究发现，弓内特征 主要是上颌弓形态，例如宽度（h2 16–100％），长度（h2 42–100％）和形状（h2 42–90％）和拥挤，主要是下颌弓（h2 35–81％） ），受到潜在的遗传力影响。与牙弓间关系有关的特征，如过喷射，咬合，后牙咬合和矢状磨牙关系，似乎不是遗传决定的。对于所有结果，证据的确定性均被评为低。尽管较弱，但现有证据表明，遗传因素是影响弓内特性的决定因素，即弓的形态和拥挤程度。可能由于它们在功能上相关，所以与上颌和下颌关系有关的咬合特征似乎具有决定性的环境因素。在这种情况下，