On using the far-infrared radiation system, whether the irradiation effect is thermal or non-thermal is controversial. We irradiated amyloid peptides that are causal factors for amyloidosis by using a submillimeter wave from 420 GHz gyrotron. Fluorescence reagent assay, optical and electron microscopies, and synchrotron-radiation infrared microscopy showed that the irradiation increased the fibrous conformation of peptides at room temperature for 30 min. The temperature increase on the sample was only below 5 K, and a simple heating up to 318 K hardly induced the fibril formation. Therefore, the amyloid aggregation was driven by the far-infrared radiation with little thermal effect.

中文翻译：

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420 GHz回旋管亚毫米波对淀粉样肽的体外辐照作用

在使用远红外辐射系统时，辐射效果是热的还是非热的存在争议。我们使用来自420 GHz回旋管的亚毫米波辐射了淀粉样蛋白肽，它们是淀粉样变性病的致病因素。荧光试剂分析，光学和电子显微镜检查以及同步加速器辐射红外显微镜显示，在室温下照射30分钟可增加肽的纤维构象。样品的温度升高仅低于5 K，简单加热至318 K几乎不会引起原纤维形成。因此，淀粉样蛋白的聚集是由远红外辐射驱动的，几乎没有热效应。