Diffusion Magnetic Resonance Imaging (MRI) plays a very important role in studying biological tissue cellular structure and functioning both in health and disease. Proper interpretation of experimental data requires the development of theoretical models that connect the diffusion MRI signal to salient features of tissue microstructure at the cellular level. In this short review, we present some theoretical approaches to describing diffusion-attenuated magnetic resonance signals. These range from the models based on statistical properties of water molecules diffusing in the tissue- cellular environment, to models allowing exact analytical calculation of the magnetic resonance signal in a specific single-compartment environment. Such theoretical analysis gives important insights into mechanisms contributing to the formation of diffusion magnetic resonance signal and its connection to biological tissue cellular structure.

中文翻译：

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生物组织中扩散衰减磁共振信号的理论模型

扩散磁共振成像 (MRI) 在研究生物组织细胞结构和健康和疾病功能方面发挥着非常重要的作用。对实验数据的正确解释需要开发理论模型，将扩散 MRI 信号与细胞水平的组织微观结构的显着特征联系起来。在这篇简短的评论中，我们提出了一些描述扩散衰减磁共振信号的理论方法。这些范围从基于在组织细胞环境中扩散的水分子的统计特性的模型，到允许在特定单室环境中对磁共振信号进行精确分析计算的模型。