The surface with high-aspect-ratio nanostructure is observed to possess the bactericidal properties, where the physical interaction between high-aspect-ratio nanostructure could exert sufficient pressure on the cell membrane eventually lead to cell lysis. Recent studies in the interaction mechanism and reverse engineering have transferred the bactericidal capability to artificial surface, but the biomimetic surfaces mimicking the topographical patterns on natural resources possess different geometrical parameters and surface properties. The review attempts to highlight the recent progress in bactericidal nanostructured surfaces to analyze the prominent influence factors and cell rupture mechanism. A holistic approach was utilized, integrating interaction mechanisms, material characterization, and fabrication techniques to establish inclusive insights into the topographical effect and mechano-bactericidal applications. The experimental work presented in the hydrogel material field provides support for the feasibility of potentially broadening applications in soft contact lenses.

中文翻译：

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用于杀菌软隐形眼镜的仿生功能表面。


观察到具有高纵横比纳米结构的表面具有杀菌特性，其中高纵横比纳米结构之间的物理相互作用可以对细胞膜施加足够的压力，最终导致细胞裂解。最近在相互作用机制和逆向工程方面的研究已将杀菌能力转移到人造表面上，但模仿自然资源地形图案的仿生表面具有不同的几何参数和表面特性。该综述试图重点介绍杀菌纳米结构表面的最新进展，分析其突出影响因素和细胞破裂机制。采用整体方法，整合相互作用机制、材料表征和制造技术，以建立对地形效应和机械杀菌应用的包容性见解。水凝胶材料领域的实验工作为软性隐形眼镜潜在拓宽应用的可行性提供了支持。