Abstract A simple and efficient method has been developed for the synthesis of thioesters from carboxylic acids and thiols using N,N'-diisopropylcarbodiimide (DIC). The reactions were carried out in water as an environmentally friendly and green solvent. The developed procedure presents an economic, efficient, mild, and very simple protocol for thioesterification reaction in aqueous media. Graphical Abstract

中文翻译：

---

N,N'-二异丙基碳二亚胺在水中形成硫酯键的新方法

摘要 开发了一种使用 N,N'-二异丙基碳二亚胺 (DIC) 从羧酸和硫醇合成硫酯的简单有效方法。反应在作为环境友好和绿色溶剂的水中进行。所开发的程序为水性介质中的硫酯化反应提供了一种经济、高效、温和且非常简单的方案。图形概要