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Grinding induced catalyst free, multicomponent synthesis of Indoloindole pyrimidine
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2020-08-31 , DOI: 10.1016/j.tetlet.2020.152383
Suresh Kumar Maury , Savita Kumari , Ambuj Kumar Kushwaha , Arsala Kamal , Himanshu Kumar Singh , Dhirendra Kumar , Sundaram Singh

A simple, efficient, environmentally friendly, and ethanol assisted mechanochemical approach for the synthesis of Indoloindole pyrimidine has been developed through a simple mortar and pestle under catalyst-free grinding method. The present protocol is green and associated with easy workup step, high yield of product, short reaction time, and bear an extensive range of functional groups.



中文翻译:

研磨诱导的无催化剂的吲哚并吲哚嘧啶的多组分合成

通过简单的研钵和杵在无催化剂的研磨方法下,开发了一种简单,高效,环保和乙醇辅助的机械化学方法来合成吲哚并吲哚嘧啶。本方案是绿色的,并且与后处理步骤容易,产物的产率高,反应时间短以及具有广泛的官能团有关。

更新日期:2020-09-20
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