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Effects of design, porosity and biodegradation on mechanical and morphological properties of additive-manufactured triply periodic minimal surface scaffolds.
Journal of the Mechanical Behavior of Biomedical Materials ( IF 3.9 ) Pub Date : 2020-08-31 , DOI: 10.1016/j.jmbbm.2020.104064
Pedram Karimipour-Fard 1 , Amir H Behravesh 1 , Holly Jones-Taggart 2 , Remon Pop-Iliev 1 , Ghaus Rizvi 1
Affiliation  

The main aim of this paper is to assess the impacts of design, porosity, and biodegradation on the mechanical and morphological properties of triply periodic minimal surface (TPMS) scaffolds. The TPMS scaffolds were designed and manufactured with different porosities by using fused deposing modeling (FDM) technique. The biodegradation test on the scaffolds was performed for four and six months. The mechanical properties were assessed employing ASTM standard compression test and an in-situ mechanical testing stage. Microcomputed tomography (Micro-CT) technique was used to investigate detailed morphological properties of the scaffolds in 3D. Results indicate that the Schwarz-D scaffolds exhibit the highest compressive strength in lower porosity scaffolds but lose mechanical properties when the porosity was increased. On the contrary, Gyroid scaffolds maintain their strength as the porosity was increased. In addition, Gyroid scaffolds preserve a higher percentage of their compressive strength after six months of biodegradation. It was also observed that biodegradation phenomenon transformed the mechanical failure mode of the scaffolds from ductile to brittle. Morphological analysis of the scaffolds revealed detailed information, which support and clarify the observed variations in the mechanical properties.



中文翻译:

设计,孔隙率和生物降解对加成制造的三重周期性最小表面支架的力学和形态学特性的影响。

本文的主要目的是评估设计,孔隙率和生物降解对三重周期性最小表面(TPMS)支架的力学和形态学特性的影响。TPMS支架是通过使用熔融沉积建模(FDM)技术设计和制造的,具有不同的孔隙率。对支架的生物降解测试进行了四个和六个月。机械性能使用ASTM标准压缩测试和原位机械测试阶段进行评估。使用微计算机断层扫描(Micro-CT)技术研究3D支架的详细形态学特性。结果表明,Schwarz-D脚手架在较低孔隙度的脚手架中显示出最高的抗压强度,但当孔隙率增加时会失去机械性能。反之,随着孔隙率的增加,甲状腺支架保持其强度。另外,在六个月的生物降解后,Gyroid支架保留了更高百分比的抗压强度。还观察到生物降解现象将支架的机械破坏模式从韧性转变为脆性。支架的形态分析揭示了详细的信息,这些信息支持并阐明了所观察到的机械性能变化。

更新日期:2020-09-08
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