BACKGROUND AND PURPOSE Bottom shuffling is a locomotion strategy that precedes independent walking in some infants. Shuffling babies are generally considered to have favorable outcomes. The aim of the present study was to reveal clinical features and neurodevelopmental outcomes of shuffling babies who visited a child developmental center. METHODS We studied 48 shuffling babies who visited Toyota Municipal Child Development Center from April 2007 to March 2015. We excluded patients with cerebral palsy, Down syndrome, or congenital disorders. In 2018, we retrospectively reviewed the clinical charts of the enrolled children. We investigated family history, neurological findings, and the developmental outcome during the follow-up period. RESULTS During the follow-up period, 20 children (42%) were diagnosed with ASD. Gross motor development in infancy was not different between infants with and without ASD. The rate of poor eye contact at the first visit and a delay in the first word speech were significantly higher in infants with ASD than in infants without ASD. A family history of bottom shuffling was significantly less frequent in infants with ASD (10%) than in those without (39%). CONCLUSION Some of bottom shufflers may represent ASD during follow-up. Paying attention to social and cognitive functions in shuffling babies is important.

中文翻译：

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洗牌婴儿和自闭症谱系障碍

背景和目的 底部改组是一种先于某些婴儿独立行走的运动策略。洗牌婴儿通常被认为具有良好的结果。本研究的目的是揭示访问儿童发育中心的洗牌婴儿的临床特征和神经发育结果。方法 我们研究了 2007 年 4 月至 2015 年 3 月访问丰田市儿童发展中心的 48 名洗牌婴儿。我们排除了脑瘫、唐氏综合症或先天性疾病的患者。2018年，我们回顾性地审查了入组儿童的临床图表。我们调查了家族史、神经系统发现和随访期间的发育结果。结果 在随访期间，20 名儿童 (42%) 被诊断出患有 ASD。患有 ASD 和不患有 ASD 的婴儿在婴儿期的粗大运动发育没有差异。与非 ASD 婴儿相比，患有 ASD 的婴儿在第一次就诊时眼神接触不良和第一个词说话延迟的比率显着更高。患有 ASD 的婴儿 (10%) 的底部改组家族史的频率明显低于没有 ASD 的婴儿 (39%)。结论 在随访期间，一些底部洗牌者可能代表 ASD。在洗牌婴儿时注意社交和认知功能很重要。患有 ASD 的婴儿 (10%) 的底部改组家族史的频率明显低于没有 ASD 的婴儿 (39%)。结论 在随访期间，一些底部洗牌者可能代表 ASD。在洗牌婴儿时注意社交和认知功能很重要。患有 ASD 的婴儿 (10%) 的底部改组家族史的频率明显低于没有 ASD 的婴儿 (39%)。结论 在随访期间，一些底部洗牌者可能代表 ASD。在洗牌婴儿时注意社交和认知功能很重要。