The kidneys are susceptible to adverse effects from many diseases, including several that are not tissue-specific. Acute kidney injury is a common complication of systemic diseases such as diabetes, lupus, and certain infections including the novel coronavirus (SARS-CoV-2). Microfluidic devices are an attractive option for disease modeling, offering the opportunity to utilize human cells, control experimental and environmental conditions, and combine with other on-chip devices. For researchers with expertise in microfluidics, this brief perspective highlights potential applications of such devices to studying SARS-CoV-2-induced kidney injury.

中文翻译：

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微流体在病毒感染相关急性肾损伤中的潜在应用。


肾脏容易受到许多疾病的不利影响，包括一些非组织特异性的疾病。急性肾损伤是糖尿病、狼疮和某些感染（包括新型冠状病毒（SARS-CoV-2））等全身性疾病的常见并发症。微流体设备是疾病建模的一个有吸引力的选择，提供了利用人体细胞、控制实验和环境条件以及与其他片上设备结合的机会。对于具有微流体专业知识的研究人员来说，这个简短的观点强调了此类设备在研究 SARS-CoV-2 诱导的肾损伤方面的潜在应用。