Cytogenetic and Molecular Study of an Adult Sclerosing Rhabdomyosarcoma of the Extremity: MYOD1-mutation and Clonal Evolution.,Cancer Genomics & Proteomics

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Cytogenetic and Molecular Study of an Adult Sclerosing Rhabdomyosarcoma of the Extremity: MYOD1-mutation and Clonal Evolution.
Cancer Genomics & Proteomics ( IF 2.6 ) Pub Date : 2020-8-30 , DOI: 10.21873/cgp.20212
Ludmila Gorunova ₁ , Bodil Bjerkehagen _{2,

3,

4} , Francesca Micci ₅ , Sverre Heim _{3,

5} , Ioannis Panagopoulos ₅

Affiliation

Spindle cell/sclerosing rhabdomyosarcoma is a genomically heterogeneous, uncommon subtype of rhabdomyosarcoma, particularly rare in adults. Its MYOD1-mutant variant is aggressive irrespective of age. Cytogenetic data on spindle cell/sclerosing rhabdomyosarcoma are sparse and disparate.

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