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Cytogenetic and Molecular Study of an Adult Sclerosing Rhabdomyosarcoma of the Extremity: MYOD1-mutation and Clonal Evolution.
Cancer Genomics & Proteomics ( IF 2.6 ) Pub Date : 2020-8-30 , DOI: 10.21873/cgp.20212
Ludmila Gorunova 1 , Bodil Bjerkehagen 2, 3, 4 , Francesca Micci 5 , Sverre Heim 3, 5 , Ioannis Panagopoulos 5
Affiliation  

Spindle cell/sclerosing rhabdomyosarcoma is a genomically heterogeneous, uncommon subtype of rhabdomyosarcoma, particularly rare in adults. Its MYOD1-mutant variant is aggressive irrespective of age. Cytogenetic data on spindle cell/sclerosing rhabdomyosarcoma are sparse and disparate.

中文翻译:

成人肢端硬化横纹肌肉瘤的细胞遗传学和分子研究:MYOD1突变和克隆进化。

梭形细胞/硬化性横纹肌肉瘤是基因组上异质的,不常见的横纹肌肉瘤亚型,在成年人中尤为罕见。其MYOD1突变体变体具有侵略性,与年龄无关。梭形细胞/硬化性横纹肌肉瘤的细胞遗传学数据稀疏且完全不同。
更新日期:2020-08-31
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