Titanium (Ti) and its alloys are widely used in dental implants due to their favorable mechanical properties and biocompatibility. Surface characteristics, including physical and chemical properties, are crucial factors to enhance the osteogenesis performance of Ti. The aim of this study is to evaluate amino group surface modification to facilitate the osteogenic potential and bone repair of dental implants both in vitro and in vivo . Herein, amino group-modified Ti surfaces were constructed via the plasma-enhanced chemical vapor deposition (PECVD) technique with an allylamine monomer. The adhesion, proliferation, alkaline phosphate activity and osteogenesis-related genetic expression of MG-63 cells on the surfaces were performed in vitro and presented a significant increase in amino group-modified Ti compared with that in Ti. The in vivo study in miniature pigs was evaluated through micro-computed tomography analysis and histological evaluation, which...

中文翻译：

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通过等离子体增强化学气相沉积改性钛的成骨性能：体外和体内研究。

钛 (Ti) 及其合金由于其良好的机械性能和生物相容性而广泛用于牙科植入物。表面特性，包括物理和化学特性，是提高 Ti 成骨性能的关键因素。本研究的目的是评估氨基表面改性，以促进体外和体内牙种植体的成骨潜力和骨修复。在此，氨基改性的 Ti 表面是通过等离子体增强化学气相沉积 (PECVD) 技术与烯丙胺单体构建的。在体外对MG-63细胞表面的粘附、增殖、碱性磷酸盐活性和成骨相关基因表达进行了研究，与Ti相比，氨基修饰的Ti显着增加。