Analysis of the T cell receptor repertoire is rapidly entering the general toolbox used by researchers interested in cellular immunity. The annotation of T cell receptors (TCRs) from raw sequence data poses specific challenges, which arise from the fact that TCRs are not germline encoded, and because of the stochastic nature of the generating process.

中文翻译：

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Decombinator V4 - 一种改进的 AIRR 兼容软件包，用于 T 细胞受体序列注释。


T 细胞受体库的分析正在迅速进入对细胞免疫感兴趣的研究人员使用的通用工具箱。从原始序列数据中对 T 细胞受体 (TCR) 进行注释提出了特定的挑战，这是由于 TCR 不是种系编码的事实以及生成过程的随机性。