The aim of this study was to determine the effects of short and long-term RFR exposure on ABR by evaluating lipid peroxidation and antioxidant status in adult rats. Sixty male albino Wistar rats were randomly divided into four groups. S1:1 week sham, S10:10 weeks sham, E1:1 week RFR, E10:10 weeks RFR. Experimental group rats were exposed to RFR 2 h/day, 5 days/week during the test period. Sham rats were kept in the same conditions without RFR. After the experiment, ABRs were recorded from the mastoids of rats using tone burst acoustic stimuli. Biochemical investigations in rat brain and ultrastructural analysis in temporal cortex were performed. ABR wave I latency prolonged in E1-group and shortened in E10-group compared to their shams. TBARS level increased in E1-group, decreased in E10-group, on the contrary, SOD and CAT activities and GSH level decreased in E1-group, increased in E10-group compared to their sham groups. Edema was present in the neuron and astrocyte cytoplasms and astrocyte end-feet in both E1 and E10 groups. Our results suggest that 900 MHz RFR may have negative effects on the auditory system in acute exposure and no adverse effects in chronic exposure without weekends.

这项研究的目的是通过评估成年大鼠脂质过氧化和抗氧化状态来确定短期和长期RFR暴露对ABR的影响。60只雄性白化Wistar大鼠随机分为四组。S1：1周假，S10：10周假，E1：1周RFR，E10：10周RFR。在测试期间，实验组大鼠每天2小时，5天/周暴露于RFR。假大鼠在没有RFR的条件下保持相同的条件。实验后，使用音爆声刺激从大鼠的乳突中记录ABR。进行了大鼠脑的生化研究和颞皮质的超微结构分析。与它们的假肢相比，E1组的ABR波I潜伏期延长，而E10组的ABR波潜伏期缩短。相反，E1组的TBARS水平升高，E10组的TBARS水平降低，与假手术组相比，E1组的SOD，CAT活性和GSH水平降低，E10组增加。E1和E10组的神经元和星形胶质细胞质以及星形胶质细胞终末存在水肿。我们的结果表明，900 MHz RFR在急性暴露下可能会对听觉系统产生负面影响，而在没有周末的情况下，慢性暴露则不会对听觉系统造成不利影响。