Parvovirus B19 (B19V) infection is well known for its mild, self‐limiting clinical presentations in children, such as erythema infectiosum. Approximately 40% of women of childbearing age are susceptible to B19V infection. While maternal B19V infection usually has a good prognosis, B19V can cause severe fetal anaemia and pregnancy loss due to its ability to suppress erythroid progenitor cells. Non‐invasive ultrasound monitoring for fetal anaemia is usually performed if maternal seroconversion occurs in the first 20 weeks of gestation, with amniocentesis for fetal infection reserved for those who first present with fetal anaemia or hydrops of unknown cause. Intrauterine transfusion is the standard treatment for severe fetal anaemia and is associated with a significant improvement in survival. However, survivors of hydrops fetalis may have a higher rate of long‐term neurodevelopmental complications compared with non‐hydropic survivors. This review aims to synthesise published data on the diagnosis, surveillance and outcomes of congenital parvovirus infection to assist clinicians in diagnosing and managing this important condition.

中文翻译：

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先天性细小病毒 B19 感染的识别和管理。

细小病毒 B19 (B19V) 感染以其在儿童中的轻微、自限性临床表现而闻名，例如传染性红斑。大约 40% 的育龄妇女容易感染 B19V。虽然母体 B19V 感染通常预后良好，由于 B19V 能够抑制红细胞祖细胞，因此 B19V 可导致严重的胎儿贫血和流产。如果在妊娠的前 20 周内发生母体血清转换，通常对胎儿贫血进行无创超声监测，而胎儿感染的羊膜穿刺术则保留给那些最初出现胎儿贫血或不明原因水肿的人。宫内输血是严重胎儿贫血的标准治疗方法，可显着提高生存率。然而，与非水肿幸存者相比，胎儿水肿幸存者可能有更高的长期神经发育并发症发生率。本综述旨在综合已发表的诊断数据，