A new anionic dendrimer (D1) has been synthesized and characterized by modification of a poly(amidoamine) (PAMAM) dendrimer with 3-(6-nitro-1,3-dioxo-1H-benzo[de]isoquinolin-2(3 H)-yl)propanoic acid (NI1). Its photophysical characteristics have been investigated in organic solvents of different polarity and a positive solvatochromism has been observed. The effect of the pH medium on the fluorescence intensity has been investigated and it has been shown that in the highly alkaline medium the dendrimer emits intense fluorescence. The dendrimer and its monomeric structural analogue have been loaded on a cotton fabric and the release of substances from the surface of the cotton fabric has been investigated. The compounds have been screened for antimicrobial and cytotoxic activities. They have been found more active against Gram-positive bacteria. The dendrimer exhibits slightly lower activity than the monomeric analogue, but is found to be significantly less cytotoxic. The deposited on cotton fabric D1 prevents the formation of bacterial biofilm on the fabric surface.

合成了一种新的阴离子树状聚合物（D1），并通过用3-（6-硝基-1,3-二氧代-1H-苯并[de]异喹啉-2（3 H）修饰聚（酰胺基胺）（PAMAM）树状聚合物进行表征）-基）丙酸（NI1）。已在不同极性的有机溶剂中研究了其光物理特性，并观察到正溶剂溶变色。已经研究了pH介质对荧光强度的影响，并且已经表明，在高碱性介质中，树枝状聚合物发出强烈的荧光。树枝状聚合物及其单体结构类似物已被装载到棉织物上，并且已经研究了物质从棉织物表面的释放。已经针对化合物的抗微生物和细胞毒性活性进行了筛选。已发现它们对革兰氏阳性细菌更具活性。树枝状聚合物显示出比单体类似物稍低的活性，但是发现其细胞毒性明显较小。沉积在棉织物D1上可防止在织物表面上形成细菌生物膜。