In pharmacy, semisynthetic antibiotics with beta-lactam ring are the most prominently used drugs. The use of these drugs for humans and animals is continuously expanding. Their presence in the water system even at low concentrations can prove to be fatal to living beings. Also, they can even grow antibiotic-resistant bacteria and thus elimination of such drugs becomes very essential. Our study is focused on batch experiments for adsorptive removal of ampicillin (AMP) and its cumulative release in different solutions using xanthan gum-cl-poly(itaconic acid)/bentonite (XG-cl-poly(IA)/BN) nanocomposite hydrogel. It was synthesized by facile microwave method. The adsorption data of AMP was analyzed using various isotherm models such as Langmuir, Freundlich, Temkin and kinetic models such as Pseudo-first order, Pseudo-second order and Intraparticle diffusion. The maximum adsorption capacity as determined from Langmuir model was 245.09 mg/g at 318 K and solution pH 7. Also, XG-cl-poly(IA)/BN nanocomposite hydrogel was evaluated for AMP release in distilled water and at different pH solutions (2.2, 5.4, 7.4 and 9.4). The maximum AMP release was observed at pH 2.2 (37%).

在药房中，带有β-内酰胺环的半合成抗生素是最常用的药物。这些药物在人类和动物中的用途正在不断扩大。它们在水系统中的存在，即使浓度很低也可能对生命造成致命的伤害。而且，它们甚至可以生长具有抗药性的细菌，因此消除此类药物变得非常重要。我们的研究集中于批实验用于吸附移除氨苄西林（AMP），并在不同的解决方案，使用黄原胶-CL-聚（衣康酸），其累积释放/膨润土（XG- CL-poly（IA）/ BN）纳米复合水凝胶。它是通过简便的微波方法合成的。使用各种等温模型（例如Langmuir，Freundlich，Temkin）和动力学模型（例如伪一级，伪第二级和粒子内扩散）分析AMP的吸附数据。根据Langmuir模型确定的最大吸附容量在318 K和溶液pH为7时为245.09 mg / g。此外，还评估了XG- cl -poly（IA）/ BN纳米复合水凝胶在蒸馏水中和不同pH溶液中的AMP释放量（ 2.2、5.4、7.4和9.4）。在pH 2.2（37％）下观察到最大的AMP释放。