Lemon myrtle leaves were extracted with ethanol at different temperatures (25, 50, and 80 °C) and times (2, 4, 6, and 10 h) to examine the effect of extraction conditions on total polyphenol contents (TPC), total flavonoid contents (TFC), their antioxidant, anti-inflammatory activities, and amount of phenolic compounds. Under optimal extraction conditions (80 °C and 6 h), the values were 23.37%, 102.72 mg gallic acid equivalents (GAE/g dry basis), 23.37 mg rutin equivalents (RE/g dry basis), 83.31%, 60.13%, and 1.10% for yield, TPC, TFC, DPPH, ABTS radical scavenging activity, and reducing power, respectively. In addition, total amount of the phenolic compounds of extract was determined as 43.9 μg/g. The anti-inflammatory effect was determined in lipopolysaccharide-stimulated RAW 264.7 cells and inhibited the production of inflammatory mediators such as nitric oxide (NO). These results indicate that extracts of lemon myrtle leaves have potential as a valuable natural product with antioxidant and anti-inflammatory.

在不同温度（25、50 和 80 °C）和时间（2、4、6 和 10 小时）下用乙醇提取柠檬香桃木叶，以检查提取条件对总多酚含量 (TPC)、总黄酮的影响含量 (TFC)、它们的抗氧化、抗炎活性和酚类化合物的含量。在最佳提取条件（80 °C 和 6 h）下，值分别为 23.37%、102.72 mg 没食子酸当量（GAE/g 干基）、23.37 mg 芦丁当量（RE/g 干基）、83.31%、60.13%、产率、TPC、TFC、DPPH、ABTS 自由基清除活性和还原能力分别为 1.10%。此外，提取物中酚类化合物的总量测定为43.9 μg/g。在脂多糖刺激的 RAW 264 中测定了抗炎作用。7 细胞并抑制炎症介质如一氧化氮 (NO) 的产生。这些结果表明柠檬桃金娘叶提取物具有作为具有抗氧化和抗炎作用的有价值的天然产品的潜力。