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Fabrication and characterization of three-dimensional porous cornstarch/n-HAp biocomposite scaffold
Bulletin of Materials Science ( IF 1.9 ) Pub Date : 2020-08-29 , DOI: 10.1007/s12034-020-02217-0
C Y Beh , E M Cheng , N F Mohd Nasir , M S Abdul Majid , M R Mohd Roslan , K Y You , S F Khor , M J M Ridzuan

The aim of this study is to investigate the morphological, functional group, crystallinity and mechanical properties of a three-dimensional porous cornstarch/n-HAp (nano-hydroxyapatite) biocomposite scaffold. In this study, cornstarch/n-HAp scaffolds were fabricated using the solvent casting and particulate leaching technique. The porous cornstarch/n-HAp composites with various cornstarch contents (30, 40, 50, 60, 70, 80 and 90 wt%) were prepared and characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffractometer and compression test. The morphology of the scaffolds possessed macropores (200–600 μm) and micropores (50–100 μm) with a high interconnectivity. The porosity of the porous cornstarch/n-HAp scaffolds varied between 53 and 70% with compressive strength and compressive modulus of 2.03 and 8.27 MPa, respectively. The results suggested that highly porous cornstarch/n-HAp scaffold properties with adequate mechanical properties can be obtained for applications in bone tissue engineering.

中文翻译:

三维多孔玉米淀粉/n-HAp生物复合支架的制备与表征

本研究的目的是研究三维多孔玉米淀粉/n-HAp(纳米羟基磷灰石)生物复合支架的形态、官能团、结晶度和机械性能。在这项研究中,玉米淀粉/n-HAp 支架是使用溶剂浇铸和颗粒浸出技术制造的。制备了不同玉米淀粉含量(30、40、50、60、70、80和90 wt%)的多孔玉米淀粉/n-HAp复合材料,并通过扫描电子显微镜、傅里叶变换红外光谱、X射线衍射仪和压缩试验进行表征. 支架的形态具有高互连性的大孔(200-600 μm)和微孔(50-100 μm)。多孔玉米淀粉/n-HAp 支架的孔隙率在 53% 到 70% 之间变化,压缩强度和压缩模量分别为 2.03 和 8。分别为 27 兆帕。结果表明,可以获得具有足够机械性能的高多孔玉米淀粉/n-HAp 支架特性,可用于骨组织工程。
更新日期:2020-08-29
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